Nalline

Along the way, in the 1940s or so, there was the discovery of the first narcotic antagonists, nalorphine or Nalline, which will reverse opioid overdose but not quite as dramatically as naloxone will.

Law enforcement in California and other states used Nalline, the brand name for nalorphine, to detect whether someone’s pupil size changed.

The Nalline programs were used to fight particular opioid epidemics in, say, East L.A. or Northern California.

You said naloxone was developed in the 1960s, so a little bit after these Nalline tests entered the scene.

The solution, California's Bureau of Narcotic Enforcement believes, lies in a narcotic antagonist called N-allylnormor-phine, known commercially as Nalline.