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folinic acid

[ foh-lin-ik ]

noun

Biochemistry, Pharmacology.
  1. a crystalline, slightly water-soluble solid, C 20 H 23 N 7 O 7 , produced by fermentation or derived from folic acid, used in medicine in the treatment of certain anemias.


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Word History and Origins

Origin of folinic acid1

First recorded in 1945–50; fol(ic) + -in 2 + -ic
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Example Sentences

Examples have not been reviewed.

She was advised to immediately stop taking methotrexate and Enbrel and begin high doses of folinic acid, which counters the effects of methotrexate.

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Pregnant women who make these antibodies may be able to mitigate this risk by taking folinic acid or other forms of folate that pass into the womb or brain via a different mechanism, the researchers say.

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In a small clinical trial, researchers randomly assigned 23 nonverbal children with autism to take folinic acid daily for 12 weeks, and 25 nonverbal children with autism to take a placebo.

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The children who took folinic acid showed more improvement in verbal communication, as measured by standardized tests, than those who took the placebo.

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A fifth study reported results from a small clinical trial suggesting that folinic acid — a form of folic acid — can ease language and communication difficulties in people with autism.

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